If the solute and the solvent can absorb the visible light, the solution yielded can have color.įor solid substances dissolving in a solvent, shaking and stirring can expedite the dissolution process. The intermolecular forces of the solute will be broken with ease. Dissolution is a kinetic process, so the kinetic energy resulting from increased temperature will speed up the process of dissolving a solute in a solvent. There are factors that can expedite the dissolution and these include the temperature. The solution formed by dissolution process is often a uniform one. Gas solvents can only dissolve gas solutes. Amongst other solvents, water is the universal solvent that is good in dissolving many substances. For instance, a polar substance may not dissolve in a non-polar solvent. However, for the substances to dissolve in a solvent, both the solute and the solvent must be compatible. This is the process through which solid, gaseous or liquid substances dissolve in a solvent to produce a solution. Some disintegration tests are done with simulated gastric or intestinal fluid to see how the dosages will perform when ingested.
Disintegration time is the time needed for the drug to break into fragments under certain conditions. The disintegration process breaks down the drug into tiny fragments or granules to improve its solubility. For any dosage to be absorbed by the body, it has to be in a solution. In the pharmaceutical industry, there is a disintegration test undertaken on drugs to make them ready for absorption into the blood stream. At times the process of disintegration can integrate with dissolution where a solid substance disintegrates into small pieces while dissolving in a solvent until it forms a uniform solution of the solute and the solvent. Compounds are disintegrated in chemical reactions. Disintegration is a process with which substances are broken down into tiny fragments to improve their solubility. To disintegrate a substance involves breaking it into small chunks, particles and molecules. The article discerns the confusion of the difference between these closely related processes. This attempt is done for quality purposes to improve the solubility and bioavailability of, for instance, pharmaceutical drugs into the blood stream.
Dissolution and disintegration are the two common processes mainly used in pharmaceutical and chemical industries to break the intermolecular and intra-molecular forces that hold substances together.
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